在线工具

bepaly买球lncrnas2路径-根据全球网络传播方法识别受感兴趣的一组lncrnas影响的路径

长非编码Rbepaly买球NA(lncrnas)已被证明在不bepaly买球同的细胞过程和生物学功能中起着重要作用。Exploring the functions associated with bepaly买球lncRNAs may help provide insight into their underlying biological mechanisms.目前的方法主要集中在研究单个lncRNa的功能;bepaly买球however,essential biological functions may be affected by the combinatorial effects of multiple bepaly买球lncRNAs.在这里,…

Read More »

intnetlncsim——一种推断人lncrna功能相似性的综合网络分析方法

越来越多的证据表明,长的非编码RNA(lncrnas)通过与mrnas/mirnbepaly买球as相互通信参与各种生物学过程和复bepaly买球杂疾病。利用lncrnas与mRNa/mirnas之间的相互作用来研究lbepaly买球ncrnas的功能,预测新的lncrna疾病相关性是一种有效的方法。哈尔滨医科大学的研究人员提出了一个综合框架,IntNetLncSim为了…

Read More »

新工具预测蛋白质和RNA的相互作用

环球化研究人员开发出全球得分,一种方法,for the first time,预测蛋白质与长非编码RNA的相互作用。bepaly买球该算法帮助科学家为实验验证确定绑定伙伴的优先级,这将有助于我们理解长非编码RNA在正常细胞功能和疾病中的作用。bepaly买球Far from just reading the information contained in the ...

Read More »

lncpricnet–通过多级复合网络对候选疾病lncrnas进行全球优先排序bepaly买球

lncRNA

bepaly买球LncRNAs play pivotal roles in many important biological processes,但是,对lncRNas在人类疾病中的作用的研究还处于起步阶段。bepaly买球Therefore,对可能与疾病相关的lncRNa进行优先排序是非常紧迫的bepaly买球。上海交通大学的研究人员开发了一种新的算法,LncPriCNet它使用一个多层次的复合网络来确定候选网络的优先级…bepaly买球

Read More »

Urb-RIP – An Adaptable and Efficient Approach for Immunoprecipitation of bepaly买球lncRNAs and Associated RNAs/Proteins

基因表达的转录后调控是一个重要的过程,是由mRNAs和RNA结合蛋白(rbp)相互作用介导的。bepaly买球非编码RNA(NCRNA)或核糖核蛋白(RNP)。Key to the study of post-transcriptional regulation of mRNAs and the function of ncRNAs such as long bepaly买球non-coding RNAs (bepaly买球lncRNAs) is an understanding of what factors are interacting with these transcripts.当几个…

Read More »

Slncky – evolutionary analysis across mammals reveals distinct classes of long bepaly买球non-coding RNAs

lncRNA

转录组测序的最新进展使得在许多物种中发现了数千个长的非编码RNA(lncrnas)。bepaly买球bepaly买球尽管几种lncRNa在不同的生bepaly买球物学过程中发挥了重要作用,the functions and mechanisms of most bepaly买球lncRNAs remain unknown.两个重要的障碍是转录组测序和lncrnas的功能特征:从基因表达谱中识别真正的非编码基因。bepaly买球bepaly买球

Read More »

annolnc–用于系统地注释新人类lncrna的Web服务器bepaly买球

lncRNA

Long noncoding RNAs (bepaly买球lncRNAs) have been shown to play essential roles in almost every important biological process through multiple mechanisms.尽管人类lncrnas的剧目迅速扩大,bepaly买球它们的生物学功能和调节在很大程度上仍然难以确定,需要一个系统的、综合的注释工具。Here researchers from Peking University present AnnoLnc,一个一站式的门户,用于系统地注释小说《人类》…

Read More »

DeepLNC,a long bepaly买球non-coding RNA prediction tool using a deep neural network

lncRNA

长非编码RNA(lncrnas)在各种细胞功能中的重要作用bepaly买球,bepaly买球such as gene imprinting,免疫反应,胚胎多能性,tumorogenesis,以及基因调控,has been widely studied and reported in recent years.Several experimental and computational methods involving genome-wide search and screenings of ncRNAs are being proposed utilizing sequence features-length,发生,以及具有各种限制的碱的组成。研究人员。。。

Read More »