Tag Archives:长非编码Rbepaly买球NA

某些lncrna类中RNA结合蛋白位点的显著富集

长非编码Rbepaly买球NA(lncrnas)bepaly买球据报道广泛参与各种调节作用,并表现出许多疾病相关性。bepaly买球lncrnas通过与细胞内其他生物分子(包括DNA)的相互作用来调节其功能。RNA,和蛋白质。RNA结合蛋白(RBP)的基因组规模实验数据集的可用性促使我们了解lncrnas在以下方面的作用:bepaly买球

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Long bepaly买球non-coding RNAs in ischemic stroke

LNCRNA

中风是全世界导致死亡和残疾的主要原因之一。揭示脑卒中的细胞和分子病理生理过程一直是当务之急。长非编码(bepaly买球LNC)RNA在各种疾病中起着关键作用。近年来,大量异常表达的lncrnas已被筛选出在缺血性卒中患者或缺血损bepaly买球伤动物中使用…

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长非编码RNA在心血管疾病中的作用及治疗潜力bepaly买球

The popularization of genome-wide analyses and RNA sequencing led to the discovery that a large part of the human genome,在有效转录的同时,不编码蛋白质。在正常和疾bepaly买球病状态下,长的非编码RNA已经成为基因表达的关键调节因子。研究心脏中表达的长非编码RNA,bepaly买球结合基因关联研究,透露…

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Microarray expression profiling of long bepaly买球non-coding RNAs in epithelial ovarian cancer

LNCRNA

Although numerous long bepaly买球non-coding RNAs (bepaly买球lncRNAs) have been identified to be important in human cancer,their potential regulatory roles in epithelial tumorigenesis and tumor progression in ovarian cancer remain unclear.南京医科大学的研究人员开始研究上皮性卵巢癌中差异表达的lncRNas,并探讨其潜在功能。bepaly买球lncrna配置文件分为五对…

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Long bepaly买球Non-Coding RNAs in Cardiac Remodeling

LNCRNA

心脏重塑发生在心脏受到压力后,manifested as pathological processes,including hypertrophy and apoptosis of cardiomyocytes,dysfunction of vascular endothelial cells and vascular smooth muscle cells as well as differentiation and proliferation of fibroblasts,ultimately resulting in progression of cardiovascular diseases.新的证据表明,长的非编码RNA(lncrnas)是心脏功能强大和动态的调节因子。bepaly买球bepaly买球

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intnetlncsim——一种推断人lncrna功能相似性的综合网络分析方法

Increasing evidence indicated that long bepaly买球non-coding RNAs (bepaly买球lncRNAs) were involved in various biological processes and complex diseases by communicating with mRNAs/miRNAs each other.Exploiting interactions between bepaly买球lncRNAs and mRNA/miRNAs to lncRNA functional similarity (LFS) is an effective method to explore function of lncRNAs and predict novel lncRNA-disease associations.哈尔滨医科大学的研究人员提出了一个综合框架,IntNetLncSim,to ...

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bepaly买球LncRNAs – macromolecules with big roles in neurobiology and neurological diseases

长非编码RNA(lncrnas)最近被定义bepaly买球为数千个长度超过200个核苷酸的RNA分子,在哺乳动物中缺乏一个可感知的开放阅读框架。尽管lncrnasbepaly买球缺乏蛋白质编码功能,它们在细胞内几乎所有蛋白质编码基因的调节中起着关键作用,包括染色质的修饰。转录和转录后处理。所以不是…

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家蚕与野生蚕丝腺长非编码RNA的鉴定与比较bepaly买球

LNCRNA

在长期的人工选择下,家蚕(家蚕)与野生家蚕相比,产量大幅度提高。曼达林家蚕。然而,the molecular mechanism of silk yield increase is still unknown.Comparative analysis of long bepaly买球non-coding RNAs (bepaly买球lncRNAs) may provide some insights into understanding this phenotypic variation.In this study,利用丝腺的RNA序列数据…

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长非编码RNA在子宫内膜癌中的新作用bepaly买球

LNCRNA

人类基因组被广泛转录,大约98%的基因组是非编码的。bepaly买球Long bepaly买球non-coding RNAs (bepaly买球lncRNAs) are a heterogeneous group of RNA transcripts that are >200 nucleotides in length with minimal to no protein-coding potential.类似于蛋白质,bepaly买球lncrnas在正常细胞和包括多种癌症在内的疾病状态中都具有重要的生物学功能。这篇评论总结了…

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